What is the general pathology associated with type two diabetes?

Type 2 Diabetes Mellitus (T2DM) is one of the most common metabolic disorders worldwide and its development is primarily caused by a combination of two main factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond to insulin [1].

What is Type 1 diabetes pathophysiology?

Pathophysiology. Type 1 DM is the culmination of lymphocytic infiltration and destruction of insulin-secreting beta cells of the islets of Langerhans in the pancreas. As beta-cell mass declines, insulin secretion decreases until the available insulin no longer is adequate to maintain normal blood glucose levels.

What is diabetes explain in detail types and pathophysiology of diabetes?

Diabetes is a group of diseases in which the body doesn’t produce enough or any insulin, doesn’t properly use the insulin that is produced, or exhibits a combination of both. When any of these things happens, the body is unable to get sugar from the blood into the cells. That leads to high blood sugar levels.

What is the physiological cause of diabetes?

Type 2 diabetes is primarily the result of two interrelated problems: Cells in muscle, fat and the liver become resistant to insulin. Because these cells don’t interact in a normal way with insulin, they don’t take in enough sugar. The pancreas is unable to produce enough insulin to manage blood sugar levels.

What pathophysiology means?

Definition of pathophysiology : the physiology of abnormal states specifically : the functional changes that accompany a particular syndrome or disease.

What is the pathophysiology of type 1 and type 2 diabetes?

Type 1 diabetes is due to pancreatic islet B cell destruction predominantly by an autoimmune process, and these persons are prone to ketoacidosis. While type 2 diabetes is the more prevalent form and results from insulin resistance with a defect in compensatory insulin secretion.

What is Type 4 Diabetes?

Type 4 diabetes is the proposed term for diabetes caused by insulin resistance in older people who don’t have overweight or obesity. A 2015 study with mice suggested this type of diabetes might be widely underdiagnosed. This is because it occurs in people who aren’t overweight or obese, but are older in age.

What are 3 types of diabetes?

There are three main types of diabetes: type 1, type 2, and gestational diabetes (diabetes while pregnant).

• Type 1 Diabetes. Type 1 diabetes is thought to be caused by an autoimmune reaction (the body attacks itself by mistake) that stops your body from making insulin.
• Type 2 Diabetes.
• Gestational Diabetes.

What are 3 causes of diabetes?

It’s clear that certain factors increase the risk, however, including:

• Weight. The more fatty tissue you have, the more resistant your cells become to insulin.
• Inactivity.
• Family history.
• Race or ethnicity.
• Age.
• Gestational diabetes.
• Polycystic ovary syndrome.
• High blood pressure.

What is an example of pathophysiology?

Pathophysiology: Deranged function in an individual or an organ due to a disease. For example, a pathophysiologic alteration is a change in function as distinguished from a structural defect.

What is the physiology of type 2 diabetes?

Pathology of type 2 diabetes. In type 2 diabetes, the body either produces inadequate amounts of insulin to meet the demands of the body or insulin resistance has developed. Insulin resistance refers to when cells of the body such as the muscle, liver and fat cells fail to respond to insulin, even when levels are high.