What is the difference between tolerance and ignorance?

Both tolerance (a process in which reactive CD8+ T cells are removed by apoptosis) or ignorance (a process in which autoreactive T cells do not respond to antigens in the islet) can occur. However, it has been unclear why some antigens induce one process but other antigens produce the other. Kurts et al.

What does it mean to tolerate someone?

If you tolerate a situation or person, you accept them although you do not particularly like them. She can no longer tolerate the position that she’s in. Synonyms: endure, stand, suffer, bear More Synonyms of tolerate.

What is immunological ignorance?

Immunological ignorance is defined as a phenomenon in which fully com- petent T cells fail to mount productive immune responses in vivo despite. From: Current Clinical Oncology: Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done.

What is tolerance and understanding?

Tolerance for those who are different from us or disagree with us allows us to recognize challenges in our own health care settings and to strive to improve upon those challenges. Understanding is the ability to walk in other people’s shoes and to comprehend their needs, perspectives, and desires.

What is an immune privileged tissue?

Privileged tissues include the brain, eye, pregnant uterus, and the testis. Initially, privilege was attributed to deficient lymphatic drainage in such tissues, or physical barriers that prevented immune cells from gaining access (Barker and Billingham 1977).

What causes T Anergy?

The anergy in T cells can be induced by Ionomycin, the ionophore capable of raising intracellular concentration of calcium ions artificially. Conversely, Ca+II chelators such as EGTA can sequester Calcium ions making them unable to cause the anergy.

What does tolerance mean to you?

Let’s begin with some abbreviated Wikipedia definitions: Tolerance is a fair, objective, and permissive attitude toward those whose opinions, practices, race, religion, nationality, etc., differ from one’s own; freedom from bigotry.

What is the difference between acceptance and tolerance?

Acceptance goes a step beyond tolerance. If a sign of tolerance is a feeling of “I can live with X (behavior, religion, race, culture, etc.),” then acceptance moves beyond that in the direction of “X is OK.” You can tolerate something without accepting it, but you cannot accept something without tolerating it.

Is tolerance a substitute for understanding?

Tolerance and/or acceptance are desirable, but they are not a substitute for understanding. They are relevant for getting along with others in the world (though understanding helps), but understanding is essential for the social and behavioral sciences article continues after advertisement

What does toleration mean in politics?

When we tolerate an activity, we resist our urge to forcefully prohibit the expression of activities that we find unpleasant. More abstractly, toleration can be understood as a political practice aiming at neutrality, objectivity, or fairness on the part of political agents.