What can I use instead of acetic anhydride?

Try propionic Anhydride it should work .

Would acetic acid be used in the esterification instead of acetyl chloride Why or why not?

Explanation: The Fischer esterification of an acid is an equilibrium reaction. To get a good yield of ester you must use a large excess of acetic acid and/or remove the water as it is formed. Acetyl chloride and acetic anhydride are both more reactive than acetic acid.

What is the best choice of acetylating agent in the synthesis of aspirin?

Concentrated phosphoric acid will be used to keep everything in the acidified, protonated state. Acetic anhydride is the preferred acid derivative to synthesize aspirin commercially because the acetic acid produced in this reaction can be used again, by converting it back into acetic anhydride.

How can you tell the difference between acetyl chloride and acetic anhydride?

Acetyl chloride is a chloride substitute of acetic acid and acetic anhydride is formed when two moles of acetic acid are mixed and a water molecule is abstracted from it. Acetic anhydride is an anhydrous form of two moles of acetic acid.

How can acetyl chloride be converted to acetic anhydride?

The most common acid halide is acetyl chloride; like acetic anhydride, acetyl chloride reacts spontaneously with an alcohol to form an ester. It will similarly react with acetic acid to form acetic anhydride (Fig.

Why do we use Ethanoic anhydride instead of Ethanoyl chloride?

Ethanoic anhydride is safer to use than ethanoyl chloride. It is less corrosive and not so readily hydrolysed (its reaction with water is slower). Ethanoic anhydride doesn’t produce dangerous (corrosive and poisonous) fumes of hydrogen chloride.

Can acetic acid be used in esterification?

The chemical structure of the alcohol, the acid, and the acid catalyst used in the esterification reaction all effect its rate. He also noted that simple acids such as acetic acid or vinegar (CH3CO2H) form esters very easily.

Is acetic acid the same as acetic anhydride?

Acetic acid is an organic compound that is very useful in different organic synthesis reactions. The key difference between glacial acetic acid and acetic anhydride is that glacial acetic acid is the most concentrated form of acetic acid, whereas acetic anhydride is the dehydrated form of acetic acid.

Why do we used acetic acid instead of acetic anhydride in the synthesis of aspirin?

Aspirin can be made by reacting salicylic acid with acetic acid in the presence of an acid catalyst. If acetic anhydride is used instead of acetic acid, the reaction is much faster and has a higher yield (since acetic anhydride is much more reactive than acetic acid).

Does acetic acid react with acetyl chloride?

Acetyl chloride is a reagent for the preparation of esters and amides of acetic acid, used in the derivatization of alcohols and amines. One class of acetylation reactions are esterification.