Q&A

Why is the mucus of a CF patient probably thicker than someone without CF?

Why is the mucus of a CF patient probably thicker than someone without CF?

In people with CF, mucus. In CF, the mucus is often thick and sticky. becomes thick and sticky because of problems with the cystic fibrosis transmembrane conductance regulator (CFTR) protein.

Is CF dominant or recessive?

This condition is inherited in an autosomal recessive pattern , which means both copies of the gene in each cell have mutations.

How does the CFTR gene work?

The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane conductance regulator. This protein functions as a channel across the membrane of cells that produce mucus, sweat, saliva, tears, and digestive enzymes.

Why Does CF happen?

Cystic fibrosis occurs when both genes in the pair have a mutation. A person with cystic fibrosis inherits one CF gene from each parent. Cystic fibrosis is a genetic disorder caused by inheriting a pair of genes that are mutated or not working properly.

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What color is mucus with cystic fibrosis?

Really dark brown, tenacious phlegm is seen in patients who have cystic fibrosis or bronchiectasis, which is a chronic lung disease. The phlegm is brown because of blood and the intense chronic inflammation that comes with the chronic disease state.

Can you have a mild form of cystic fibrosis?

Atypical CF is a milder form of the CF disorder, which is associated with mutations of the cystic fibrosis transmembrane receptor gene. Instead of having classic symptoms, individuals with atypical CF might only have mild dysfunction in 1 organ system and might or might not have elevated sweat chloride levels.

Why can’t people with cystic fibrosis be near each other?

For people with CF, being close to others with the disease puts them at greater risk of getting and spreading dangerous germs and bacteria. This is called cross‐infection. Not only are these dangerous germs difficult to treat, but they can also lead to worsening symptoms and faster decline in lung function.

Is CF a Sexlinked trait?

Cystic fibrosis is an autosomal recessive disorder, meaning that is not inherited solely from the mother or father as in sex-linked disorders. Rather, cystic fibrosis is inherited when an individual receives a mutated copy of the gene associated with cystic fibrosis from both parents.

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What chromosome is the CF gene on?

The seventh pair of chromosomes has a gene called the CFTR (cystic fibrosis transmembrane conductance regulator) gene. Changes (mutations) or errors in this gene are what cause CF.

What gene has been the target of CF gene therapy What does this gene normally do?

Gene therapy for the treatment of cystic fibrosis should be a “natural”: Cystic fibrosis (CF) is a recessive disease associated with loss of function mutations in the CF transmembrane conductance regulator (CFTR) gene, which has a well-characterized gene product; heterozygotes, as predicted, appear to be phenotypically …

Why does CF cause salty skin?

As CF is caused by a faulty gene that controls the movement of chloride and water into and out of cells, people with CF often sweat more than people without the condition, and this sweat contains high levels of chloride, which can crystallise into salt visibly on the skin.

Can you get cystic fibrosis at any age?

While cystic fibrosis is usually diagnosed in childhood, adults with no symptoms (or mild symptoms) during their youth can still be found to have the disease.

Why does the g-π relationship exist?

That clearly isn’t pi squared. Why does this g -π relationship exist? It has to do with the definition of the meter. Before that, let’s look at the Seconds pendulum. This is a pendulum that takes exactly 1 second to go from one side of its motion to the other (or a 2 second period).

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Why is g = π2 related to the seconds pendulum?

In that case, I have to have g = π 2. That’s why these values are related. The seconds pendulum was one of the ways to define the length of one meter. Of course, there are other ways to define this length.

Does [math]π^2 [/math] equal g?

We know that the value of π as approximated is 3.1415926. If you square it, it gives 9.8696044, a value very close to the acceleration due to gravity near the surface of earth (when expressed in SI units). Meanwhile, if you say [math]π^2 [/math] equals g, I would say no. Being equal involves dimensional equality.

Why does Pi^2 equal gravity?

pi^2 does NOT equal gravity; many of the other answers are correct in either the numbers are slightly off, or there’s no units on pi-squared, or in a different measurement system we have a different number (32 ft/sec/sec, for instance).